a word of advice is to have medicines with them on the carry on bag. e.g. if say they need to take the pill every 3 hours and they mistakenly checked them into the checked bag it could be nasty if they get sick inflight
Having medicine with them in their carry on bag also causes another problem. When you go through customs / security screening some medicines require doctor / medical certificates of prove (that is is for personal use) before they can be brought outside Australia. I've seen this situation before where the pax got held up.
If they can't walk long distances and there's a possibility of them getting lost inside an airport (as passengers often do), request a wheelchair or assistance from the airline prior to the day of the flight. Even if they don't need wheelchairs to bring them to the gate, if they require assistance in navigating their way through the terminal in Sydney they could perhaps be led by a ground staff who may push another wheel chair passenger
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